Fig. 2

LncRNA expression profile in NOZ/Dox cells. a The scatter plot was used for assessing the variation in lncRNA expression between NOZ/Dox and NOZ/Ctrl cells. The values of x and y axes in the scatter plot were the normalized signal values of the samples (log2 scaled). The gray dotted lines are fold-change lines. The lncRNAs above the top gray dotted line and below the bottom gray dotted line indicated more than 2.0-fold change of lncRNAs between the two compared samples. The volcano plot was constructed using fold-change values and P-values. The vertical lines correspond to 2.0-fold up and down, respectively, and the horizontal line represents a P-value of 0.05. The green and red point in the plot represents the differentially expressed lncRNAs with statistical significance. b The cluster heat map showed the differentially expressed lncRNAs over 2.0-fold change. Red colour indicates high expression level, and green colour indicates low expression level. c The top 10 upregulated lncRNAs and top 10 downregulated lncRNAs. The arrow indicates GBCDRlnc1