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Fig. 7 | Molecular Cancer

Fig. 7

From: Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

Fig. 7

Silencing of miR-191 impairs the cell proliferation, migration and invasion abilities of HCC cells with reduced circTRIM33–12 expression. a miR-191 expression in HCC cells was modified by shRNA interference. b, c Reduced miR-191 expression enhanced TET1 protein expression but not TET1 mRNA in HCC cells. d, e The cell proliferation in HCC cells with the reduced expression of miR-191 was assessed by a CCK-8 assay. f, g The migration and invasion abilities in HCC cells with the reduced expression of miR-191 were evaluated via a transwell assay. The data are represented as the mean ± SD, n = 3. *P < 0.05; **P < 0.01; NS, no significant

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Molecular Cancer

ISSN: 1476-4598