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Table 2 Univariate and Multivariate Analyses of Factors Associated with Overall Survival

From: Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

  OS
  Multivariate
Factors Univariate, P HR 95% CI P value
Sex (female vs. male) 0.106    NA
Age (years) (≤50 vs. > 50) 0.118    NA
HBsAg (positive vs. negative) 0.730    NA
HCVAb (positive vs. negative) 0.860    NA
Liver cirrhosis (yes vs. no) 0.598    NA
Serum AFP, ng/mL (≤20 vs. > 20) 0.424    NA
Serum ALT, U/L (≤75 vs. > 75) 0.627    NA
Tumor size (diameter, cm) (> 5 vs ≤ 5) 0.004 1.172 1.066–2.750 0.026
Tumor number (multiple vs. single) 0.175    NA
TNM (III/IV vs I/II.) 0.121    NA
CircTRIM33–12 expression (high vs. low) 0.001 0.504 0.932–1.942 0.007
  1. OS overall survival, NA not adopted, AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen, 95%CI 95% confidence interval, HR hazard ratio, Cox proportional hazards regression model