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Fig. 5 | Molecular Cancer

Fig. 5

From: The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer by sponging anti-tumor miRNAs

Fig. 5

knockout of UCA1 restored PHA-stimulated T cell activation and improved the cytotoxicity of CIK therapy. a total PDL1 level was reduced in UCA1-KD GC cells. b cell surface PDL1 was detected by flow cytometry. c PHA induced PBMCs were co-cultured with UCA1-KD or control GC cells. IFNγ production in the supernatant was detected by ELISA. d knockdown of PDL1 expression in GC cells could improve the cytotoxic sensitivity to CIK therapy in vitro

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