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Fig. 7 | Molecular Cancer

Fig. 7

From: METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

Fig. 7

PTEN was negatively correlated with METTL3 expression in bladder cancer tissues. a. A moderate negative correlation between the expression of METTL3 and PTEN was showed in bladder cancer tissues by qRT-PCR. b, c, d and e. RNA and proteins was extracted from the tumors and the protein expression of METTL3/PTEN was measured using PCR and western blot. f. g. IHC analysis of ki-67, METTL3, and PTEN in xenografs (Magnification, × 400, scale bars indicated 10 μm). h. Mode pattern of the METTL3/miR221/222/PTEN regulatory network in bladder cancer

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