WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

Table 1 Clinical characteristics of 90 HCC patients depending on WTAP expression levels

Feture	WTAP-high	WTAP-low	n	Χ ²	P
All cases	45	45
Differentiation				1.113	0.291
Low	19	24	43
High	26	21	47
AJCC stage				0.194	0.66
Stage I	30	28	58
Stage II & III	15	17	32
Tumor size				0.809	0.362
≤ 5 cm	29	33	62
>5 cm	16	12	28
Tumor encapsulation				3.607	0.045*
Absent	28	19	47
Present	17	26	43
Microvascular infiltration				0.104	0.747
Absent	30	28	58
Present	10	11	21
HbsAg				0.338	0.561
Negative	8	10	18
Positive	37	34	71
HbcAb				0.09	0.765
Negative	4	3	7
Positive	41	39	80
AFP				0.647	0.421
≤ 400 μg/L	27	30	57
>400 μg/L	18	14	32
Recurrence				3.629	0.045*
No	16	25	41
Yes	29	20	49

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