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Fig. 4 | Molecular Cancer

Fig. 4

From: Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence

Fig. 4

Enforced expression of Circ-ZKSCAN1 inhibited proliferation, migration, and invasion of BCa cells in vitro. a After the overexpression of circ-ZKSCAN1, qPCR was used to detect expression of circ-ZKSCAN1 in T24 and UM-UC-3. b-c MTS assays showed that circ-ZKSCAN1 could inhibite the viablities of T24 and UM-UC-3. d-e Clony formation assays demonstrated that circ-ZKSCAN1 could inhibit the formation of clonies in T24 and UM-UC-3. f Representative images of the cell cycle analysis by using flow cytometry. g-h Circ-ZKSCAN1 arrested the UM-UC-3 and T24 cell cycle at the G1/S phase. i-j Cell migration and invasion assays were performed and measured in T24 and UM-UC-3 transfected with circ-ZKSCAN1 or vector

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