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Fig. 1 | Molecular Cancer

Fig. 1

From: LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2

Fig. 1

SATB2-AS1 expression is downregulated in CRC and is correlated with prognosis. a, Hierarchical cluster heat map of differentially expressed lncRNAs in CRC and corresponding normal tissues generated from RNA sequencing data from the TCGA database. Red in the heat map denotes upregulation; green denotes downregulation. The red line indicates SATB2-AS1. b, Expression of SATB2-AS1 in the TCGA CRC cohort, Hong CRC cohort, Marra CRC cohort and our CRC cohort 1. c, Representative images of SATB2-AS1 expression in CRC and adjacent colorectal tissues detected by ISH in our CRC cohort 1. d, SATB2-AS1 expression in CRC cell lines (HCT-116, HCT-8, HT-29, SW-480, SW-620, DLD-1 and Caco-2) compared with the normal colorectal epithelial cell NCM460 detected by qRT-PCR. e, Survival was analyzed and compared between patients with high and low levels of SATB2-AS1 expression in tumors in the corresponding CRC cohort using the Kaplan-Meier method. *, P < 0.05; **, P < 0.01 and ***, P < 0.001

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