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Fig. 2 | Molecular Cancer

Fig. 2

From: LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

Fig. 2

Correlation between expression of PVT1 and clinical characteristics. a. Higher expression of PVT1 lncRNA was significantly correlated with advanced tumor stage (T stage and N stage), as well as higher grade tumor and signet ring cell subtype. b. Kaplan-Meier analysis of OS time according to PVT1 and MYC expression level. EAC patients with higher PVT1 expression showed poorer survival than that of low expression (left). MYC expression is not associated with survival of patients with EAC. High expression was defined as ≥2 times of mean of normal tissue, whereas low expression was considered as < 2 times of mean of normal tissue. Log-rank probabilities between high and low expression were shown. Error bars, mean ± SEM. *, P < 0.05

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