Functional roles of circular RNAs during epithelial-to-mesenchymal transition

Table 2 EMT-related circRNAs acting through WNT signaling

circRNA	Expression pattern	Interaction with WNT signaling	Sponged miRNA	Cancer type	Reference
CircRNA-100290	Up	Activate	miR-516b	CRC	[74]
CircRNA-NEK6	Up	Activate	miR-370-3p	TC	[75]
Circ_0000177	Up	Activate	miR-638	Glioma	[76]
Circ_CBFB	Up	Activate	miR-607	CLL	[77]
Circ_0001946	Up	Activate	miR-13a-5p	LAC	[94]
CircRNA_102171	Up	Activate	–	PTC	[99]
Circ_0006427	Down	Inhibit	miR-6783-3p	LUAD	[80]
Circ_0000523	Down	Inhibit	miR-31	CRC	[81]
Circ-ITCH	Down	Inhibit	miR-214	Glioma	[90]
Circ-ITCH	Down	Inhibit	miR-214, miR-17	TNBC	[89]
Circ_0002052	Down	Inhibit	miR-1205	OS	[85]

CRC Colorectal cancer, TC Thyroid cancer, CLL Chronic lymphocytic leukemia, LAC/LUAD Lung adenocarcinoma, PTC Papillary thyroid cancer, TNBC Triple-negative breast cancer, OS Osteosarcoma

ISSN: 1476-4598