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Fig. 3 | Molecular Cancer

Fig. 3

From: Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals

Fig. 3

E-cadherin is involved in circ-AKT3-dependent inhibition of ccRCC cells migration and invasion. a Protein expression levels of metastasis related genes were screened through Western blotting analysis. b-c TCGA analysis of the expression levels of E-cadherin in paired and unpaired ccRCC tissues. d The schematic flowchart shows the pipelines of miRNAs which could bond to circ-AKT3 and E-cadherin 3′-UTR via online bioinformatic network. e-f the RT-PCR and qRT-PCR arrays determined that miR-296-3p, miR-382-5p and miR-326 could interact with circ-AKT3 via RNA pull down assay

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