The role of exosomal PD-L1 in tumor progression and immunotherapy

Table 1 The regulatory role of tumor cell-derived exosomes in tumor progression

Origin of Exosomes	Target cells							Tumor progression	References
Origin of Exosomes	DC	CTL	Treg	Th17	M2	NK	Monocyte	Tumor progression	References
Heat-stressed tumor cell	↑		↓	↑				↓	[20]
Hepatocellular carcinoma cell	↑	↑↓			↑	↓		↑↓	[21,22,23,24]
Malignant glioma cell	↑	↑						↓	[25]
Leukemia cell	↑	↑				↑		↓	[26, 27]
RenCa cell		↑						↓	[28]
Gastric cancer cell		↓					↑	↑	[29]
Melanoma cell		↓						↑	[16, 30, 31]

ISSN: 1476-4598