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Table 1 The function of the substance in HCC exosomes

From: The significance of exosomes in the development and treatment of hepatocellular carcinoma

Components Functions First author/s Year References
Rab protein, GTPase, annexin Membrane transport and fusion CORDONNIER M 2017 [34]
miRNA
 miR-1247-3p Promote lung migration of liver cancer Fang T 2018 [77]
 miRNA-210 Promotes angiogenesis Lin XJ 2018 [81]
 miR-103 Vascular permeability and metastasis Fang JH 2018 [83]
 miR-23a-3p Inhibits the function of T-cell Liu J 2019 [99]
 miR-122 Improve the treatment effect Lou G 2015 [117]
 miR-335 Novel therapeutic strategy Wang F 2018 [118]
 microRNA-25-5p Migration、Invasion Liu H 2018 [122]
 miR-320a-PBX3 Proliferation、metastasis Zhang Z 2017 [123]
 miR-718 Prediction the prognosis of HCC Sugimachi K 2015 [124]
 miR-665 Biomarker Qu Z 2017 [125]
HSP
 HSP70, HSP60 and HSP90 Diagnosis and treatment CORDONNIER M 2017 [34]
 lncRNA HOTAIR The release of exosomes YANG L 2019 [45]
 RNA and DNA Regulation cell genetics and epigenetics ZHANG X 2015 [71]
 Vps4A Tumor suppressor Jin-xing Wei 2015 [76]
lncRNA
 lncRNA-ATB Novel prognosis of biomarker and therapeutic targets Lee YR 2019 [110]
 LUCAT1 and CASC9 Biomarker Gramantieri L 2018 [126]
circRNA
 circ-DB Promote HCC growth and reduce DNA damage Zhang H 2019 [79]
 circPTGR1 Clinical stage and prognosis Wang G 2019 [113]
  1. HCC hepatocellular carcinoma, miR/miRNA micro ribonucleic acid, HSP heat shock proteins, circRNA Circular RNAs, lncRNA Long noncoding ribonucleic acid