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Table 5 MiRNAs and other drugs resistance in HCC

From: The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

MiRNAs Expression1 Pathway Drug Reference
miR-16 down-regulated IKBKB paclitaxel [35]
miR-9 down-regulated eIF-5A-2 cetuximab [112]
miR-23a down-regulated Topoisomerase 1(TOP1) etoposide [113]
miR-26b down-regulated Mcl-1 TRAIL [114]
miR-138 down-regulated interferon stimulating gene 15 TRAIL [115]
miR-93 up-regulated PTEN; CDKN1A tivantinib [50]
  1. 1miRNAs either up-regulated or down-regulated in other chemo-drugs resistant hepatocellular carcinoma cells
  2. Note: This table shows 6 miRNAs, their expression level and potential targets in chemoresistance of hepatocellular carcinoma