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Table 5 MiRNAs and other drugs resistance in HCC

From: The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

MiRNAs

Expression1

Pathway

Drug

Reference

miR-16

down-regulated

IKBKB

paclitaxel

[35]

miR-9

down-regulated

eIF-5A-2

cetuximab

[112]

miR-23a

down-regulated

Topoisomerase 1(TOP1)

etoposide

[113]

miR-26b

down-regulated

Mcl-1

TRAIL

[114]

miR-138

down-regulated

interferon stimulating gene 15

TRAIL

[115]

miR-93

up-regulated

PTEN; CDKN1A

tivantinib

[50]

  1. 1miRNAs either up-regulated or down-regulated in other chemo-drugs resistant hepatocellular carcinoma cells
  2. Note: This table shows 6 miRNAs, their expression level and potential targets in chemoresistance of hepatocellular carcinoma