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Table 6 LncRNAs and drug resistance in HCC

From: The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

LncRNAs Expression1 Pathway Drugs Reference
NR2F1-AS1 up-regulated miR-363-ABCC1 oxaliplatin [131]
HANR up-regulated GSKIP/P-GSK3β adriamycin [132]
lncARSR up-regulated PTEN-PI3K/Akt adriamycin [134]
HULC up-regulated USP22/Sirt1/ autophagy oxaliplatin;5-FU; pirarubicin [135]
MALAT1 up-regulated miR-216b/ autophagy 5-FU; adriamycin;mitomycin [136]
TUC338 up-regulated RASAL1 sorafenib [137]
VLDLR up-regulated ABCG2 sorafenib [138]
  1. 1lncRNAs either up-regulated or down-regulated in chemo-resistant hepatocellular carcinoma cells
  2. Note: This table shows 7 lncRNAs, their expression level and underlying pathways in the chemoresistance of hepatocellular carcinoma