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Table 6 LncRNAs and drug resistance in HCC

From: The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

LncRNAs

Expression1

Pathway

Drugs

Reference

NR2F1-AS1

up-regulated

miR-363-ABCC1

oxaliplatin

[131]

HANR

up-regulated

GSKIP/P-GSK3β

adriamycin

[132]

lncARSR

up-regulated

PTEN-PI3K/Akt

adriamycin

[134]

HULC

up-regulated

USP22/Sirt1/ autophagy

oxaliplatin;5-FU; pirarubicin

[135]

MALAT1

up-regulated

miR-216b/ autophagy

5-FU; adriamycin;mitomycin

[136]

TUC338

up-regulated

RASAL1

sorafenib

[137]

VLDLR

up-regulated

ABCG2

sorafenib

[138]

  1. 1lncRNAs either up-regulated or down-regulated in chemo-resistant hepatocellular carcinoma cells
  2. Note: This table shows 7 lncRNAs, their expression level and underlying pathways in the chemoresistance of hepatocellular carcinoma