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Fig. 5 | Molecular Cancer

Fig. 5

From: Long noncoding RNA LCAT1 functions as a ceRNA to regulate RAC1 function by sponging miR-4715-5p in lung cancer

Fig. 5

miR-4715-5p inhibits lung cancer cell proliferation, migration, invasion, and cell cycle. a miR-4715-5p expression in lung cancer cells transfected with control miRNA or miR-4715-5p mimics was quantified by qRT-PCR. b, c The inhibitory effect of miR-4715-5p mimic on cell proliferation was evaluated using a CCK8 assay and a colony formation assay. d Migration and invasion ability of lung cancer cells transfected with control miRNA or miR-4715-5p mimics. e, f Cell cycle profile of lung cancer cells transfected with control miRNA or miR-4715-5p mimics. g, h Western blot analysis of cell cycle-related proteins in cells overexpressing miR-4715-5p. i, j Growth curve and colony formation in lung cancer cells co-transfected with si-LCAT1 and miR-4715-5p inhibitor

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Molecular Cancer

ISSN: 1476-4598