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Fig. 1 | Molecular Cancer

Fig. 1

From: Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression

Fig. 1

Domains and crystal structures of FOXP family. a Domains of FOXP1, FOXP2, FOXP3 and FOXP4. FOXP members share a highly conserved C2H2 zinc finger domain, leucine zipper domain, Forkhead DNA binding domain and about 50 residues N terminal domain. Also, FOXP1 and FOXP2 contain CtBP1 binding domain different from FOXP3 and FOXP4. b Crystal structures of FOXP1 (PDB: 2KIU), FOXP2-DNA complex (PDB: 2A07) and FOXP3-DNA complex (PDB:3QRF) by using The PyMOL Molecular Graphics System Version 2.3.0

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