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Fig. 2 | Molecular Cancer

Fig. 2

From: Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells

Fig. 2

Effects of forced circFGFR1 expression on the progression of the NSCLC cells. a and b NSCLC cell proliferation after the expression of circFGFR1 was upregulated, as assessed by CCK-8 assay (a) and clonal formation assay (b). c and d NSCLC cell migration and invasion after the expression of circFGFR1 was upregulated, as assessed by wound-healing assay (c) and Matrigel Transwell assay (d). e and f Tumor growth and metastatic ability of NSCLC cells with the upregulated circFGFR1 expression was investigated in nude mice xenograft tumor models. The data are presented as the mean ± SD, *P < 0.05, **P < 0.01

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