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Fig. 5 | Molecular Cancer

Fig. 5

From: Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells

Fig. 5

Knocking out CXCR4 reverses the oncogenic effect of circFGFR1 in the NSCLC cells in vitro. a and b Proliferation of CXCR4-knockout NSCLC cells with upregulated circFGFR1 expression was assessed by CCK-8 assay (a) and clonal formation assay (b). c and d Cell migration and invasion of the CXCR4-knockout NSCLC cells with upregulated circFGFR1 expression was assessed by wound-healing assay (c) and Matrigel Transwell assay (d). The data are presented as the mean ± SD. NS: not significant

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