Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells

Table 2 Univariate and Multivariate Analyses of Factors Associated with Overall Survival

Factors	OS
	Univariate, P	Multivariate
	Univariate, P	HR	95% CI	P value
Sex (Female vs. Male)	0.372			NA
Age (years) (≤ 60 vs. > 60)	0.821			NA
Smoking status (Smokers vs. Nonsmokers)	0.117			NA
Histological type (SCC vs. Adenocarcinomas)	0.061			NA
Lymph node metastasis (Yes vs. No)	0.026			NS
Differentiation (Well and moderate vs. Poor)	0.014			NS
Tumor size (diameter, cm) (> 3 vs. ≤ 3)	0.007	1.417	1.094–2.217	0.031
TNM (III-IV vs. I-II)	0.056			NA
CircFGFR1 expression (High vs. Low)	0.002	1.574	0.911–1.927	0.013

OS Overall survival, NA Not adopted, NS Not significantly, SCC Squamous cell carcinoma, 95%CI 95% confidence interval, HR Hazard ratio; Cox proportional hazards regression model

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