Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells

Table 3 Univariate and Multivariate Analyses of Factors Associated with Cumulative Recurrence

Factors	Cumulative Recurrence
	Univariate, P	Multivariate
	Univariate, P	HR	95% CI	P value
Sex (Female vs. Male)	0.414			NA
Age (years) (≤ 60 vs. > 60)	0.871			NA
Smoking status (Smokers vs. Nonsmokers)	0.332			NA
Histological type (SCC vs. Adenocarcinomas)	0.087			NA
Lymph node metastasis (Yes vs. No)	0.074			NA
Differentiation (Well and moderate vs. Poor)	0.062			NA
Tumor size (diameter, cm) (> 3 vs. ≤ 3)	0.037			NS
TNM (III-IV vs. I-II)	0.016			NS
CircFGFR1 expression (High vs. Low)	0.006	1.443	1.077–2.824	0.023

NA Not adopted, NS Not significantly, SCC Squamous cell carcinoma, 95%CI 95% confidence interval, HR hazard ratio; Cox proportional hazards regression model

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