Fig. 4From: The emerging role of SPOP protein in tumorigenesis and cancer therapyThe tumor suppresssive role of SPOP in human cancers. SPOP suppresses tumorigenesis and progression via regulation of cell growth, apoptosis, migration, invasion and drug resistance by targeting its downstream substrates in several types of human malignancies, including prostate, lung, gastric, liver, colon and endometrial cancersBack to article page