miR-1305 rescues the tumor progressive role of circRIP2. To prove tumor suppressive role of circRIP2 could be rescued by miR-1305. miR-1305 and miR-nc were introduced together into circRIP2 over-expressed and control cells. a, b. qPCR was taken to evaluate circRIP2, RIP2, miR-1305 expression; c, d. CCK8 assay was performed to detect cell viability of bladder cancer cells; e, f. Cell potential to replicate and self-renew was reflected by clone formation; g, h. Rate of wound healing assay showed cell potential of migration; scale bar: 100 μm. i, j, k, l, m. Trans-well migration and matrigel invasion assay showed cell potential of migration and invasion of bladder cancer cells; scale bar: 25 μm.