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Fig. 5 | Molecular Cancer

Fig. 5

From: circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Fig. 5

miR-1305 rescues the tumor progressive role of circRIP2. To prove tumor suppressive role of circRIP2 could be rescued by miR-1305. miR-1305 and miR-nc were introduced together into circRIP2 over-expressed and control cells. a, b. qPCR was taken to evaluate circRIP2, RIP2, miR-1305 expression; c, d. CCK8 assay was performed to detect cell viability of bladder cancer cells; e, f. Cell potential to replicate and self-renew was reflected by clone formation; g, h. Rate of wound healing assay showed cell potential of migration; scale bar: 100 μm. i, j, k, l, m. Trans-well migration and matrigel invasion assay showed cell potential of migration and invasion of bladder cancer cells; scale bar: 25 μm.

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