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Table 2 Relationship between circRIP2 level and clinical characteristics in bladder cancer

From: circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Total

Patients

Expression of circRIP2

High

Low

p

Age (mean)

53.21

51.32

50.27

0.713

Gender

 Male

46

20

26

0.614

 Female

12

5

7

 

Tumor stage

 Tis/Ta/T1

33

13

20

0.038

 T2

16

8

8

 

 T3/T4

9

4

5

 

Grade

 High

34

9

25

0.002

 Low

24

16

8

 

Number of tumors

 Solitary

41

22

19

0.584

 Multiple

17

3

14

 

Metastasis

 N0 M0

28

17

11

0.012

 N1 M0

18

8

10

0.009

 N1 M1

12

0

12

 

Follow-up(month, mean)

33.23

31.83

33.67

0.024a

  1. p < 0.05 represents statistical significance (Chi-square test)
  2. a Results are analyzed by Kaplan-Meier curves and log-rank test