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Fig. 4 | Molecular Cancer

Fig. 4

From: Circular RNA CRIM1 functions as a ceRNA to promote nasopharyngeal carcinoma metastasis and docetaxel chemoresistance through upregulating FOXQ1

Fig. 4

CircCRIM1 promotes NPC cell metastasis and EMT by relieving miR-422a repression of FOXQ1 expression. a Representative and quantified results of the Transwell migration and invasion assays for S18 cells cotransfected with either si-circCRIM1 or scrambled control and miR-422a inhibitor or miRNA inhibitor control. b Representative and quantified results of the Transwell assays for S26 cells cotransfected with either circCRIM1 overexpression plasmid or vector and FOXQ1 siRNA or scrambled control. c-d Western blotting analysis of FOXQ1, E-cadherin, Vimentin and α-tubulin expression. Mean (n = 3) ± S.D. Student’s t-tests; *P < 0.05. Scale bar, 100 μm

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Molecular Cancer

ISSN: 1476-4598