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Fig. 6 | Molecular Cancer

Fig. 6

From: CircMRPS35 suppresses gastric cancer progression via recruiting KAT7 to govern histone modification

Fig. 6

CircMRPS35 Expression Parallels that of FOXO1 and FOXO3a in Gastric Cancer Tissues. a Representative IHC staining of FOXO1 and FOXO3a in gastric cancer tissues and corresponding adjacent tissues. Scale bar, 200 μm. b FOXO1 and FOXO3a expression in 160 pairs of gastric cancer and adjacent tissues. c The association between FOXO1 expression and tumor size in gastric cancer patients (P < 0.05). d The association between FOXO3a expression and TNM stage/lymphatic metastasis in gastric cancer patients (P < 0.01). e-f The ROC curves for predicting patient survival time using FOXO1 e or FOXO3a f expression. g-h Kaplan–Meier analyses of overall survival according to FOXO1 g or FOXO3a h expression levels. i-j The correlations between the expression levels of circMRPS35 and FOXO1 i or FOXO3a j (P < 0.0001). k Kaplan–Meier analyses of overall survival time according to the combination of circMRPS35 and FOXO1. (P < 0.0001). l Kaplan–Meier analyses of overall survival time according to the combination of circMRPS35 and FOXO3a. (P < 0.0001)

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