TY - JOUR AU - Liu, Kaisheng AU - Gao, Lin AU - Ma, Xiaoshi AU - Huang, Juan-Juan AU - Chen, Juan AU - Zeng, Leli AU - Ashby, Charles R. AU - Zou, Chang AU - Chen, Zhe-Sheng PY - 2020 DA - 2020/03/12 TI - Long non-coding RNAs regulate drug resistance in cancer JO - Molecular Cancer SP - 54 VL - 19 IS - 1 AB - Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs (lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug resistance. SN - 1476-4598 UR - https://doi.org/10.1186/s12943-020-01162-0 DO - 10.1186/s12943-020-01162-0 ID - Liu2020 ER -