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Fig. 1 | Molecular Cancer

Fig. 1

From: CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a

Fig. 1

a Hierarchical clustering of circRNA differential expression profiles between three EOC samples and four normal ovarian samples. The heat maps are generated from differentially expressed circRNAs (top 50). Red and green colors indicate relative expression above or below the average. b Volcano map of deferentially expressed circRNAs (top 50). c Functional analysis of differentially expressed circRNAs (top 50). d The top 50 expressed circRNAs were analyzed by KEGG pathway. (D) CircMUC16 expression was detected in 30 normal ovarian tissues and 70 EOC samples. e The expression of circMUC16 in 30 paired serum samples with normal ovarian tissues and 70 serum samples with epithelial ovarian cancer tissues. Error bars represent the standard error. The symbols * and ** show p < 0.05 and 0.01, respectively

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