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Fig. 3 | Molecular Cancer

Fig. 3

From: CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a

Fig. 3

CircMUC16-mediated autophagy promoted cellar proliferation and invasion. a, b SKOV3 cells were transfected with LV2-NC, LV2–1, LV2–1 + PCMV5-ATG5, or LV2–1 + PCMV5-Beclin1. A2780 cells were transfected with LV6-NC, LV6, LV6 + ATG5 siRNA, or LV6 + Beclin1 siRNA. Then, western blot was used to detected the expression of LC3. c-f SKOV3 cells were transfected with LV2-NC, LV2–1, LV2–1 + PCMV5-ATG5, or LV2–1 + PCMV5-Beclin1. A2780 cells were transfected with LV6-NC, LV6, LV6 + ATG5 siRNA, or LV6 + Beclin1 siRNA. Then, the cellular proliferation and invasion was detected. Error bars represent the standard error. The symbols * and ** indicate p < 0.05 and 0.01, respectively. Scale bar: 100 μm

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