Table 2 Cancer radioresistance related miRNAs

Prostate cancer

miR-205

Disturbing DNA damage repair through PKCε and ZEB1 inhibition

[149]

miR-875-5p

Regulating EMT; Suppressing EGFR-ZEB1 axis

[150]

miR-124/ miR-144

Counteracting hypoxia-induced autophagy and downregulating PIM1

[151]

miR-301a/miR-301b

Regulating miR-301a/b-NDRG2 axis

[152]

Esophageal cancer

miR-193a-3p

Reducing PSEN1

[153]

miR-301a

Targeting WNT1, counteracting the Wnt/ β-catenin signaling pathway and reversing EMT

[154]

miR-338-5p

Regulating survivin

[155]

miR-17

Regulating C6orf120

[156]

miR-98

Binding to BCL-2

[157]

miR-124

Regulating miR-124/ CDK4 axis

[158]

Nasopharyngeal carcinoma

miR-495

Binding the 3’UTR of GRP78 and inhibiting its expression

[159]

miR-24-3p

Modulating 3’UTR and 5’UTR of Jab1/CSN5

[160]

miR-24

Binding SP1

[161]

miR-150

Inhibiting GSK3β

[162]

miR-222

Interacting with PTEN

[163]

miR-19b-3p

Activating TNFAIP3/NF-κB pathway

[164]

Cervical cancer

miR-4778-3p

Negatively regulating NR2C2 and Med19 expression; Enhancing apoptosis-related genes expression

[165]

miR-15a-3p

Promoting tumor protein D52

[166]

miR-125

Downregulating CDKN1A and targeting p21

[167]

miR-424

Targeting aprataxin

[168]

miR-21

Decreasing PTEN and increasing p-Akt/HIF-1α; Inhibiting autophagy via Akt-mTOR pathway

[169]

Lung cancer

miR-198

Inhibiting HGF/c-MET pathway

[170]

miR-99a

Binding to mTOR

[171]

miR-558

Associating with AATK

[172]

miR-148b

Modulating MutL homologue 1

[173]

miR-335

Reducing the expression of PARP-1, downregulating NF-κB

[174]

miR-1246

Inhibiting DR5

[175]

miR-21

Upregulating HIF-1α

[176]

miR-208a

Targeting p21 with a corresponding activation of the Akt/mTOR pathway

[177]

Oral cancer stem cells

miR-218

Activating miR-218/Bmi1 axis

[178]

Hepatocellular carcinoma

miR-92b

Reducing p57kip2 expression

[179]

Breast cancer

miR-142-3p

Attenuating CSCs characteristics and inhibiting β-catenin expression

[180]

miR-22

Negatively modulating Sirt1

[181]

miR-668

Forming miR-668/ IκBα/NF-κB axis

[182]

Ovarian cancer

miR-214

Depressing PETN and consequently activating PI3K/Akt pathway

[183]