Fig. 4
From: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
General mechanisms for functions of circular RNAs (circRNAs). circRNAs can function as a sponge for a miRNA/RBP keeping miRNA/RBP away (dashed arrows) from its mRNA targets, thus altering gene expression. Through interaction with U1 snRNP, exon-intron circRNAs (EIciRNAs) can interact with transcription complexes at host genes to induce their transcription