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Fig. 1 | Molecular Cancer

Fig. 1

From: A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer

Fig. 1

The identification and characteristics of circFNDC3B in CC. a Divergent primer detected circular RNAs in cDNA but not gDNA. b Two exons form circFNDC3B by back splicing from chromosomal region and Sanger sequencing of circFNDC3B showed the back-splice junction (∇). c Relative RNA level of circFNDC3B and FNCDC3B mRNA treated with RNase R. d Relative RNA level of circFNDC3B and FNCDC3B mRNA in different time points. e Fluorescence in situ hybridization assay was conducted to determine the subcellular localization of circFNDC3B. f The circFNDC3B expression was significantly low in CC cells. g The circFNDC3B expression was significantly low in CC tissues compared to normal tissues. h The circFNDC3B expression was significantly low in 77% CC patients. i Kaplan–Meier’s analyses of correlations between the circFNDC3B expression levels and OS (overall survival) of 87 CC patients. ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598