Fig. 5

CircFNDC3B-218aa, not circFNDC3B inhibits the in vivo tumorigenicity ability of CC using animal experiments. a Nude mice xenografts were formed by HCT116 cells transfected with Lv-vector, Lv-circFNDC3B, Lv-circFNDC3B-mut and Lv-circFNDC3B-218aa, respectively. Tumor volumes were monitored with a caliper during the time course of 30 days, and tumor weights were also measured at the end of this study. b Representative BLI of the four groups is shown. The incidences of liver metastases in each group were shown. **P < 0.01 vs Lv-vector group; ### P < 0.001 vs Lv-circFNDC3B-mut group