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Fig. 1 | Molecular Cancer

Fig. 1

From: The network of non-coding RNAs and their molecular targets in breast cancer

Fig. 1

The network of non-coding RNAs and its targets in breast cancer. The graph shows the non-coding RNAs (in the square nodes) cited in at least 2 different sources from literature. Empty circles correspond to the coding genes. Each connecting line (or edge) indicates a publication (PMID) from PubMed. When multiple edges connect the same two RNAs in the network, then multiple publications described this interaction. The edges are directed (i.e. from the non-coding RNA to its target, being either coding or non-coding). In red are depicted the links indicating a repressive action (flat arrowhead), while in black are those showing activation (with traditional arrowhead). Dashed lines correspond to edges indicating indirect effects. The network is the essential core showing what remains after filtering the nodes (non-coding RNAs, in orange, and miRNAs, in light blue) based on their degrees (i.e. the number of connections to targets or other non-coding RNAs). The network’s details are reported in the Table 2

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