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Fig. 2 | Molecular Cancer

Fig. 2

From: CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

Fig. 2

circLONP2 correlates with metastasis and unfavorable prognosis of CRC patients. a Detection of circLONP2 in verification cohort by RT-qPCR, normalized to GAPDH (n = 97). b Kaplan-Meier survival analysis of CRC patients according to the expression level of circLONP2 using log-rank test (n = 128). c-e RNA FISH in tissue specimen showing significant circLONP2 overexpression along with the invasive margin of metastatic CRC. f Detection of circLONP2 in primary CRC tissue and paired liver metastasis, normalized to GAPDH (n = 10). All experiments were repeated for three times, data were shown as mean ± SD, * P < 0.05, ** P < 0.01 in Mann-Whitney U test (a), log-rank test (b), or paired Student’s test (f)

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Molecular Cancer

ISSN: 1476-4598