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Fig. 6 | Molecular Cancer

Fig. 6

From: Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma

Fig. 6

Downregulated CXCL12 turnovers circ_0020710-induced malignant phenotype. a-d CCK-8, Colony formation, transwell invasion and wound healing assays performed in A2058 cells treated with Vector, circ_0020710, circ_0020710 + AMD3100, and circ_0020710 + siCXCL12. e Western blot assay was used to detect the p-ERK, p-AKT, and β-catenin levels in melanoma cells following different treatments, GAPDH was used as a negative control. One-way ANOVA test and Kruskal-Wallis test were used for the statistical analyses. *p < 0.05; **p < 0.01

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Molecular Cancer

ISSN: 1476-4598