Fig. 2
From: Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer
Association between m6A and miRNAs on 3′-UTRs of mRNAs. (A) m6A is more common on 3′-UTRs of mRNAs containing miRNA target sites. m6A is mostly deposited near the stop codon, whereas miRNA target sites are generally enriched in 3′ end of 3′-UTRs (B) m6A may regulate the binding and gene silencing function of the downstream-bound miRNAs. (C) miRNAs promote METTL3-mediated m6A formation on mRNAs through a sequence pairing mechanism