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Fig. 2 | Molecular Cancer

Fig. 2

From: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

Fig. 2

High levels of circMET promote HCC progression a. The expression of circMET in HCC cells was determined by qRT-PCR; b. The expression of circMET in HCCLM3 cells was inhibited, and in HepG2 cells, it was elevated; c. The invasion abilities of HCC cells with silenced or forced expression of circMET were evaluated by a transwell assay. Left, the representative pictures of transwell assay. Right, statistic of transwell assay; d. The migration abilities of HCC cells with silenced or forced expression of circMET were evaluated by the scratch assay; e. Colony formation assays were performed in the indicated cells. Left, representative pictures of colony formation assay. Right, statistic of colony formation assay; f. Proliferation in HCC cells with silenced or forced expression of circMET was assessed by MTT assay; g. The cell cycle in HCC cells with silenced or forced expression of circMET was assessed by FCM

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Molecular Cancer

ISSN: 1476-4598