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Fig. 4 | Molecular Cancer

Fig. 4

From: Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance

Fig. 4

LncRNAs regulate autophagy-mediated chemoresistance. The process of autophagy is divided into five distinct stages: initiation, vesicle nucleation, vesicle elongation, vesicle fusion, and cargo degradation. LncRNAs act as a ceRNA, directly bind to mRNAs or proteins, and regulate autophagy-mediated multidrug resistance (MDR) by targeting ATGs or ATG-LC3 complex

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