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Table 1 Correlation between circUHRF1 and clinicopathological characteristics in 240 HCC patients

From: Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma

Variable

circUHRF1

P value

Low

High

Age (years)

   

  ≤ 50

52

57

0.604

  > 50

68

63

Sex

 Female

41

37

0.679

 Male

79

83

HBsAg

 Negative

15

9

0.282

 Positive

105

111

HCVAb

 Negative

101

107

0.343

 Positive

19

13

Liver cirrhosis

 No

71

62

0.299

 Yes

49

58

Serum AFP, ng/mL

  ≤ 20

8

17

0.089

  > 20

112

103

Serum ALT, U/L

  ≤ 75

88

75

0.097

  > 75

32

45

Tumor size (diameter, cm)

  ≤ 5

65

38

0.001

  > 5

55

82

NK cell proportion in blood

  ≤ 8%

62

84

0.005

  >  8%

58

36

Microvascular invasion

 No

67

48

0.020

 Yes

53

72

Tumor number

 Single

84

76

0.338

 Multiple

36

44

TNM

 I/II

44

52

0.356

 III/IV

76

68

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Molecular Cancer

ISSN: 1476-4598