Table 2 Univariate and multivariate analyses of factors associated with overall survival
| Â | OS | |||
|---|---|---|---|---|
| Â | Multivariate | |||
Factors | Univariate, P | HR | 95% CI | P value |
Sex (Female vs. Male) | 0.771 | Â | Â | NA |
Age (years) (≤50 vs. > 50) | 0.417 |  |  | NA |
HBsAg (Positive vs. Negative) | 0.274 | Â | Â | NA |
HCVAb (Positive vs. Negative) | 0.622 | Â | Â | NA |
Liver cirrhosis (Yes vs. No) | 0.318 | Â | Â | NA |
Serum AFP, ng/mL (≤20 vs. > 20) | 0.629 |  |  | NA |
Serum ALT, U/L (≤75 vs. > 75) | 0.811 |  |  | NA |
Tumor size (diameter, cm) (> 5 vs ≤ 5) | 0.036 | 1.622 | 1.107–2.514 | NS |
NK cell proportion in blood (≤ 8% vs. >  8%) | 0.204 |  |  | NA |
TNM (III/IV vs I/II.) | 0.071 | Â | Â | NA |
CircUHRF1 expression (High vs. Low) | 0.003 | 1.339 | 0.944–2.045 | 0.022 |