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Table 1 m6A methylation modifies ncRNAs in cancers

From: Novel insights into the interplay between m6A modification and noncoding RNAs in cancer

m6A component Related non-coding RNA Cancer Function Role in cancer Regulation References
METTL3 miR-25-3p PDAC Writers Oncogene Up-regulation [45]
miR-221、miR-222 Bladder cancer Writers Oncogene Up-regulation [46]
miR-106b, miR-18a/b, miR-3607, miR-423, miR-30a, miR-320b/d/e arsenite-induced carcinogenesis Writers Oncogene Up-regulation [47]
miR-1246 CRC Writers Oncogene Up-regulation [49]
miR-143-3p Lung cancer Writers Oncogene Up-regulation [50]
METTL14 miR-126 HCC Writers Anti-oncogene Down-regulation [48]
METTL3 lncRNA FAM225A NPC Writers Oncogene Up-regulation [67]
lncRNA LINC00958 HCC Writers Oncogene Up-regulation [65]
lncRNA RP11 CRC Writers Oncogene Up-regulation [68]
MALAT1 NSCLC Writers Oncogene Up-regulation [69]
METTL14 XIST CRC Writers Anti-oncogene Down-regulation [70]
METTL3/METTL14 LNCAROD HNSCC Writers Oncogene Up-regulation [66]
ALKBH5 lncRNA NEAT1 GC Erasers Oncogene Up-regulation [71]
lncRNA FOXM1-AS glioblastoma Erasers Oncogene Up-regulation [57]
YTHDF1 LINC00278 ESCC Readers Anti-oncogene Down-regulation [72]
IGF2BP2 lncRNA DANCR Pancreatic cancer Readers Oncogene Up-regulation [60]
  1. PDAC pancreatic ductal adenocarcinoma, HCC hepatocellular cancer, NPC nasopharyngeal cancer, GC gastric cancer, CRC colorectal cancer, NSCLC non-small cell lung cancer, HNSCC head and neck squamous cell carcinoma, ESCC esophageal squamous cell carcinoma