Table 1 m6A methylation modifies ncRNAs in cancers
From: Novel insights into the interplay between m6A modification and noncoding RNAs in cancer
m6A component | Related non-coding RNA | Cancer | Function | Role in cancer | Regulation | References |
|---|---|---|---|---|---|---|
METTL3 | miR-25-3p | PDAC | Writers | Oncogene | Up-regulation | [45] |
miR-221、miR-222 | Bladder cancer | Writers | Oncogene | Up-regulation | [46] | |
miR-106b, miR-18a/b, miR-3607, miR-423, miR-30a, miR-320b/d/e | arsenite-induced carcinogenesis | Writers | Oncogene | Up-regulation | [47] | |
miR-1246 | CRC | Writers | Oncogene | Up-regulation | [49] | |
miR-143-3p | Lung cancer | Writers | Oncogene | Up-regulation | [50] | |
METTL14 | miR-126 | HCC | Writers | Anti-oncogene | Down-regulation | [48] |
METTL3 | lncRNA FAM225A | NPC | Writers | Oncogene | Up-regulation | [67] |
lncRNA LINC00958 | HCC | Writers | Oncogene | Up-regulation | [65] | |
lncRNA RP11 | CRC | Writers | Oncogene | Up-regulation | [68] | |
MALAT1 | NSCLC | Writers | Oncogene | Up-regulation | [69] | |
METTL14 | XIST | CRC | Writers | Anti-oncogene | Down-regulation | [70] |
METTL3/METTL14 | LNCAROD | HNSCC | Writers | Oncogene | Up-regulation | [66] |
ALKBH5 | lncRNA NEAT1 | GC | Erasers | Oncogene | Up-regulation | [71] |
lncRNA FOXM1-AS | glioblastoma | Erasers | Oncogene | Up-regulation | [57] | |
YTHDF1 | LINC00278 | ESCC | Readers | Anti-oncogene | Down-regulation | [72] |
IGF2BP2 | lncRNA DANCR | Pancreatic cancer | Readers | Oncogene | Up-regulation | [60] |