Fig. 1From: Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospectsThe differentiation of Tregs in tumor from naïve T cell in thymus through circulation. Treg is derived from peripheral naive T cells induced by tumor microenvironmental signals, including tumor antigens, cytokines (such as TGF-β) and some metabolic factor, which are concluded now. Furthermore, these promotion and inhibition factors are explained in this reviewBack to article page