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Fig. 4 | Molecular Cancer

Fig. 4

From: Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer

Fig. 4

Identification of METTL14 targets via RNA-Seq and m6A-Seq. a Differentially expressed genes with over 2-fold expression changes in PANC-1 cells treated with shMETTL14 compared with those treated with shCtrl. b Top consensus motif identified from m6A-Seq peaks in PANC-1-shCtrl and PANC-1-shMETTL14 cells. c, d Number of m6A peaks and m6A-modified transcripts identified from m6A-Seq peaks in PANC-1-shCtrl and PANC-1-shMETTL14 cells. e Schematic diagram of METTL14 downstream analysis

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Molecular Cancer

ISSN: 1476-4598