Skip to main content
Fig. 5 | Molecular Cancer

Fig. 5

From: Correction to: EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis

Fig. 5

circMMP9 upregulates CDK4 and AURKA via miR-124. a Flow chart to screen the targets of miR-124 in GBM. b CDK4 and AURKA expression was detected via IHC in GBM tissues and adjacent normal tissues. c The cells positive for CDK4 and AURKA were counted (***P < 0.001). d The protein expression levels of CDK4 and AURKA were measured by western blot assays in GBM tissues and adjacent normal tissues. e CDK4 and AURKA expression was evaluated by qRT-PCR in GBM tissues with high circMMP9 expression or low circMMP9 expression (P < 0.05). f U87 cells were transfected with mock, circMMP9 plasmid, or circMMP9 plasmid and miR-124. CDK4 and AURKA expression was detected by qRT-PCR and western blot assays (***P < 0.001). g U251 cells were transfected with mock, circMMP9 siRNA1 + 2, circMMP9 siRNA1 + 2 or anti-miR-124. CDK4 and AURKA expression was detected by qRT-PCR and western blot assays (***P < 0.001)

Back to article page

Molecular Cancer

ISSN: 1476-4598