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Fig. 6 | Molecular Cancer

Fig. 6

From: Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1

Fig. 6

The expression levels of ETS1, IGF2, FOXM1 and E-cadherin and their correlation with miR-4521 expression in GC. a Comparison of ETS1, IGF2 and FOXM1 mRNA levels in GC tumors vs normal gastric tissues, N2–3 vs N0–1 GC specimens, metastatic vs non-metastatic GCs and late- vs early-stage GCs, respectively. Error bars denote SD. *P < 0.05; **P < 0.01. b miR-4521 expression inversely correlated with ETS1, IGF2 and FOXM1 expression but positively correlated with E-cadherin expression in gastric carcinoma specimens. Moreover, ETS1 expression was positively associated with IGF2 and FOXM1 but negatively associated with E-cadherin in GCs

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Molecular Cancer

ISSN: 1476-4598