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Fig. 2 | Molecular Cancer

Fig. 2

From: Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma

Fig. 2

In vitro studies of Nano-FdUMP. a) Cytotoxicity of CT26 and Hepa1–6 cells treated with 5-Fu and Nano-FdUMP (n = 3, ** p < 0.01). b) Apoptotic CT26 and Hepa1–6 cells (%) treated with PBS, 5-Fu, Nano-dUMP and Nano-FdUMP were measured by Annexin V-FTIC and PI assay (n = 3, * p < 0.05). c) The ROS level in CT26 and Hepa1–6 cells treated with PBS, 5-Fu, Nano-dUMP and Nano-FdUMP (n = 3, * p < 0.05). d) Apoptotic CT26 and Hepa1–6 cells (%) treated by Nano-FdUMP following incubation with or without NAC (n = 3, * p < 0.05 and ** p < 0.01)

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Molecular Cancer

ISSN: 1476-4598