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Fig. 1 | Molecular Cancer

Fig. 1

From: Bone marrow infiltrated natural killer cells predicted the anti-leukemia activity of MCL1 or BCL2 inhibitors in acute myeloid leukemia

Fig. 1

Overall survival (OS) of AML patients based on their BM infiltrated NK cells and its receptors KIRs. a KIRs expression levels in patients with or without FLT3 mutations. b Kaplan-Meier plots of OS for patients according to the expression level of KIRs, respectively. c The prognostic values of the KIRs factors combined with FLT3 mutation status. d OS of patients according to the BM infiltrated NK cells in training (4 missing cases) and validation cohorts (10 missing cases). e The expression of KIRs were in groups with high or low NK cells, activated and resting NK cells, respectively. Resting NK cells is colored in blue, activated NK cells in Turquoise, and bulk NK cells in green. Mean ± SEM values are shown. *P < 0.05, **P < 0.01, ***P < 0.001. f A proposed cellular model to describe the function of immune cells in patients

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Molecular Cancer

ISSN: 1476-4598