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Fig. 2 | Molecular Cancer

Fig. 2

From: Long non-coding RNA UCA1 promotes malignant phenotypes of renal cancer cells by modulating the miR-182-5p/DLL4 axis as a ceRNA

Fig. 2

Knockdown and overexpression of UCA1 inhibited or promote cell proliferation. The relative expression level of UCA1 was significantly down-regulated by shUCA1 (a) and upregulated by pcDNA3.1-UCA1(b and c). ANOVA was used for the comparison of curves of cell proliferation. Cell proliferation was detected in both renal cancer cells after transfection of shRNA (d and e) and pcDNA3.1-UCA1 (f and g). Representative images of EdU assay and the relative fold changes of EdU positive cells were detected by shRNA (H and I) and pcDNA3.1-UCA1 (j and k). Assays were performed in triplicate, and data were shown as mean ± standard deviation (SD) of those biological replicates or samples (*P < 0.05, **P < 0.01)

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