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Fig. 5 | Molecular Cancer

Fig. 5

From: lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/β-catenin signaling

Fig. 5

JPX promoted proliferation and metastasis of lung cancer cells by inhibiting miR-33a-5p. (a, b) Rescue effects of JPX overexpression on miR-33a-5p mimics-mediated inhibition of cell growth in SPP-A1 and NCI-H1299 cells determined by CCK-8 assays. (c, d) Rescue effects of JPX overexpression on miR-33a-5p mimics-mediated inhibition of cell proliferation in SPP-A1 and NCI-H1299 cells determined by colony formation assays. (e, f) Rescue effects of JPX overexpression on miR-33a-5p mimics-mediated inhibition of cell migration in SPP-A1 and NCI-H1299 cells determined by wound healing assays. (g, h) Rescue effects of JPX overexpression on miR-33a-5p mimics-mediated inhibition of cell invasion in SPP-A1 and NCI-H1299 cells determined by transwell assays. Data are shown as the mean ± SD, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598